Saturday, December 19, 2009

plus 1, Mutations in breast cancer gene linked to infertility - Newstrack India

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plus 1, Mutations in breast cancer gene linked to infertility - Newstrack India


Mutations in breast cancer gene linked to infertility - Newstrack India

Posted: 19 Dec 2009 01:52 AM PST

Washington, Dec 19 (ANI): A new study from New York Medical College has found a possible link between a breast cancer gene and infertility.

 

Lead researcher Dr Kutluk Oktay, professor of obstetrics and gynecology, showed that mutations in the BRCA1 gene, which have been linked with early onset breast cancer, are also associated with an early loss of egg reserves.

 

This might help to explain why women who carry a mutated BRCA1 gene have greater rates of infertility as well as a greater risk for breast and ovarian cancer.

 

During the study, researchers performed ovarian stimulation in 126 women with breast cancer for the purpose of fertility preservation by embryo or oocyte cryopreservation.

 

Of the 82 women, who met the inclusion criteria, 47 women had undergone BRCA testing, with 14 having a mutation in BRCA genes.

 

In BRCA mutation-positive patients, the low ovarian response rate was significantly greater than for patients who did not show BRCA gene mutations, nor for women who had not been tested for the gene at all.

 

Oktay added if fertility drugs are not as effective in stimulating egg production in the ovaries of patients who carry BRCA1 mutations, this establishes a link between infertility and the risk of getting breast or ovarian cancer.

 

The study is published in the Journal of Clinical Oncology. (ANI)

 

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GateHouse Media's Pink promotion nets $30K to fight breast cancer - Abington Mariner

Posted: 18 Dec 2009 07:01 AM PST

GateHouse Media New England's "Paint the Town Pink" program brought in more than $30,000 in green for the American Cancer Society – money that will help the group continue to make strides against breast cancer.

"One hundred-thirteen newspapers, 100 percent in pink, I don't think it's ever been done before," said Richard Daniels, the CEO of GateHouse Media New England, which published all of its papers on pink newsprint and ran a pink background for all WickedLocal.com Web sites in early October, as Breast Cancer Awareness Month began.

On Thursday, Dec. 17, Daniels presented a large pink check for $30,535.58 to Deborah Cornwall, a member of the American Cancer Society's New England division board of directors.

"It's nice when everybody does something, and that includes our readers, our advertisers – how can you not feel good about this," Daniels said.

"I'm a breast cancer survivor, so I particularly appreciate this," Cornwall said. "I really thank you for your support. This has been a great partnership."

She added that "this kind of support is just so essential to the work that we do," including eradicating breast cancer and mobilizing survivors.

Daniels also thanked Mike O'Connor of We Got Soccer, a soccer specialty store in Foxboro, for sponsoring the Paint the Town Pink program.

"It's all about the cause, and we're happy to do whatever we can to support it," O'Connor said.

Several representatives from both GateHouse and the American Cancer Society were on hand for the presentation. The money – generated from a portion of the proceeds of advertising packages and newsstand sales for the pink papers, and donations from credit card subscriptions during October – will go toward the society's Making Strides Against Breast Cancer walk, which benefits breast cancer research, education, advocacy and patient services.

Daniels, who wore a pink tie for the occasion, said the pink newsprint might be toned down by one or two shades next year.

 

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