Sunday, February 14, 2010

plus 3, Fruits, veggies slash breast cancer risk: U.S. study - Dose.ca

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plus 3, Fruits, veggies slash breast cancer risk: U.S. study - Dose.ca


Fruits, veggies slash breast cancer risk: U.S. study - Dose.ca

Posted: 14 Feb 2010 09:13 AM PST

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WASHINGTON (Reuters) - Certain breast cancer survivors who load up on fruits and vegetables, eating far more than current U.S. guidelines, can slash their risk the tumors will come back by nearly a third, according to a U.S. study released on Monday.

The finding only held for women who did not have hot flashes after their cancer therapy, the researchers said -- a finding that suggests fruits and vegetables act on estrogen.

Their analysis suggests an explanation for why some studies have shown that eating more fruits and vegetables lowers the risk that breast cancer will come back, while others do not. It may depend on the individual patient, they report in the Journal of Clinical Oncology.

"Women with early stage breast cancer who have hot flashes have better survival and lower recurrence rates than women who don't," said Ellen Gold of the University of California Davis, who helped lead the study.

Several studies have shown this. And this study showed that women who had hot flashes after treatment for breast cancer had lower estrogen levels than women who did not.

As estrogen drives the most common type of breast cancer, this suggests that eating extra servings of fruits and vegetables -- above and beyond the five servings a day recommended by the U.S. government -- may lower harmful estrogen levels in cancer survivors, the researchers said.

"It appears that a dietary pattern high in fruits, vegetables and fiber, which has been shown to reduce circulating estrogen levels, may only be important among women with circulating estrogen levels above a certain threshold," said John Pierce of the University of California San Diego.

The researchers took a second look at data from 3,000 breast cancer patients in a study aimed at seeing whether a diet low in fat and high in fruits and vegetables might keep their cancer from coming back.

Such a diet has been shown to lower overall risk of ever getting breast cancer in the first place.

The women were on average 53, and half were told to double their fruit and vegetable intake to 10 servings a day, eat more fiber and lower fat intake more than government recommendations. "We compared the dietary intervention group to a group that received '5-a-day' dietary guidelines," the researchers wrote.

About 30 percent of the original 3,000 breast cancer survivors said they did not have hot flashes -- a common side-effect of breast cancer treatment.

The researchers looked at the data on these women specifically and found that only 16 percent of those who doubled up on fruits and vegetables had their tumors come back after seven years, compared to 23 percent of those merely given advice on food guidelines.

Women who had been through menopause lowered their risk by 47 percent if they loaded up on salads, fruit and other plant food.

(Reporting by Maggie Fox; Editing by Julie Steenhuysen)

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Want to reduce breast cancer risk? Eat walnuts - Windsor Star

Posted: 14 Feb 2010 10:24 AM PST

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WASHINGTON (Reuters) - By eating walnuts, women could reduce their risk of breast cancer, researchers said on Tuesday.

Researchers at Marshall University School of Medicine in Huntington, West Virginia, found that lab mice bred to develop breast cancer had a significantly lower risk of breast cancer if fed the human equivalent of a handful of walnuts a day.

"Walnuts are better than cookies, french fries or potato chips when you need a snack," Elaine Hardman, one of the researchers working on the study, said in a statement.

"We know that a healthy diet overall prevents all manner of chronic diseases," she said.

Hardman said while the study was done with laboratory animals, likely the same mechanism would be at work in people.

"Walnuts contain multiple ingredients that, individually, have been shown to slow cancer growth including omega-3 fatty acids, antioxidants and phytosterols," Hardman's team wrote in a summary presented at the American Association for Cancer Research's annual meeting in Denver.

The researchers used specially bred mice that normally always develop breast cancer. Half got the human equivalent of two ounces of walnuts per day and half got a normal diet.

The mice eating the walnuts had fewer and smaller breast tumors and those that did get them got them later than the other mice.

"These laboratory mice typically have 100 percent tumor incidence at five months; walnut consumption delayed those tumors by at least three weeks," Hardman said in a statement.

"It is clear that walnuts contribute to a healthy diet that can reduce breast cancer."

The study adds to evidence that omega-3 fatty acids can provide a range of health benefits, from preventing heart disease to lowering cancer risks.

Scientists have been unsure whether the types found in nuts and leafy green vegetables work as well as the omega-3 fatty acids found in fish oil.

(Reporting by Deborah Charles; Editing by Maggie Fox and Paul Simao)

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Breast Cancer Fears Grow Around Household Cleaners - Daily Finance

Posted: 14 Feb 2010 10:46 AM PST

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That fresh clean smell that American's love may be boosting cases of breast cancer in the U.S.-- and possibly even causing breast cancer in young children, let alone their moms.

Doctors and environmental scientists are growing more concerned that chemicals found in many household cleaning supplies, such as floor cleaners and glass cleaners, are behind the ongoing increase in breast cancer cases in the U.S. According to the New York Times, the chances that a 50 year-old white woman will develop breast cancer has increased from 1% in 1975 to 12% today. Anecdotal evidence from some of the latest epidemiological data suggests that younger women (and a growing number of men) are contracting the cancer.

Environmental Factors Outweigh Genetics, Health

Some of this increase likely results from better detection. But many of these problems appear to stem from a person's surroundings rather than their genetics or health. For example, researchers have found that Asian women living in the U.S. have much higher rates of breast cancer than Asian women living in Asia. This implies that the problem is something environmental.

"It is highly likely that environmental toxins in air, food, dust, soil and drinking water have contributed to increasing rates of cancer in Americans of all ages, including our children," reported Dr. Philip Landrigan, Director of the Center for Children's Health and the Environment at New York's Mount Sinai School of Medicine, in testimony before Congress. "The known and suspected causes of childhood cancer include benzene, other solvents, radiation, arsenic, parental smoking, certain pesticides and certain chemicals in the environment that have the potential to disrupt the function of the endocrine system."

Household Items May Be at Fault

Other chemicals that scientists suspect of playing a role in the rise of these illnesses include simple bleach, flame retardants (many of which have been banned in Europe) and components of plastics used in packaging for food, canned goods, and, until recently, children's bottles and sippy cups. The American public may already be sensing the danger as sales of green cleaning products are skyrocketing. Industry, too, is changing its tune. Both Clorox and cleaning products company S.C. Johnson have begun to reveal ingredients lists for their products, although its still hard to ascertain the true impact of the chemicals they list due to the multiple forms these chemicals could take.

The new disclosure policies are clearly due in part to impending green labeling initiatives by retailing giant Wal-Mart (WMT) and to aggressive rating and disclosure policies by GoodGuide, an online product rating site that focuses on environmental and health impacts of household cleaners, cosmetics and health products. Cleaning products company Clorox (CLX) rolled out a green line of cleaners and the entire segment of green cleaning is growing at triple-digit rates, according to product research firm MinTel.

But many of the substances that health care experts are worried about tend to persist in the environment for many years. So even as Americans switch to a greener cleaning regime, the trends in health problems that may be resulting from these more toxic substances may not slow or reverse for decades. In other words, even if Americans can learn to ditch the happy smells, they are hardly ouf of the woods on breast cancer or other potentially deadly ailments.

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Migraines cut breast cancer risk 30 percent: Study - Dose.ca

Posted: 14 Feb 2010 05:09 AM PST

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CHICAGO (Reuters) - In a puzzling twist, women who have a history of migraine headaches are far less likely to develop breast cancer than other women, U.S. researchers said on Thursday.

The study is the first to look at the relationship between breast cancer and migraines and its findings may point to new ways of reducing a woman's breast cancer risk, they said.

"We found that, overall, women who had a history of migraines had a 30 percent lower risk of breast cancer compared to women who did not have a history of such headaches," said Dr. Christopher Li of the Fred Hutchinson Cancer Research Center in Seattle, whose findings appear in the journal Cancer Epidemiology, Biomarkers and Prevention.

Li said the reduction in risk was for the most common types of breast cancers -- those driven by hormones, such as estrogen-receptor positive breast cancer, which is fueled by estrogen, and progesterone-receptor positive breast cancer, which is fueled by progesterone.

Hormones also play a role in migraines, a brutal type of headache often accompanied by nausea, vomiting and heightened sensitivity to light and sound. Women are two to three times more likely than men to get migraines.

While it is not exactly clear why women with a history of migraines had a lower risk for breast cancer, Li and colleagues suspect hormones are playing a role.

"Women who have higher levels of estrogen in their blood have higher levels of breast cancer," Li said in a telephone interview.

And he said migraines are often triggered by low levels of the hormone estrogen, such as when estrogen levels fall during a woman's menstrual cycle.

Women who get migraines "may have a chronically lower baseline estrogen. That difference could be what is protective against breast cancer," Li said.

For the study, Li and colleagues analyzed data from two studies of 3,412 post-menopausal women in the Seattle area, 1,938 of whom had been diagnosed with breast cancer and 1,474 of whom had no history of breast cancer. Women in the study provided information on their migraine history.

They found women who had reported a clinical diagnosis of migraine had a 30 percent reduced risk of developing hormonally sensitive breast cancers.

"Migraines are typically most severe among pre-menopausal women," Li said. "This study was all post-menopausal women."

He said that suggests the protective effect seen in women who get migraines may have a lasting effect at reducing breast cancer risk.

"While these results need to be interpreted with caution, they point to a possible new factor that may be related to breast-cancer risk," Li said in a statement.

Breast cancer is the leading cause of cancer death among women worldwide, with an estimated 465,000 deaths annually, according to the American Cancer Society.

(Editing by Will Dunham and Eric Beech)

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