Monday, October 26, 2009

“M. D. Anderson redefines screening guidelines for breast, cervical and ... - Genetic Engineering News” plus 4 more

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“M. D. Anderson redefines screening guidelines for breast, cervical and ... - Genetic Engineering News” plus 4 more


M. D. Anderson redefines screening guidelines for breast, cervical and ... - Genetic Engineering News

Posted: 26 Oct 2009 10:23 AM PDT

Oct 26 2009, 1:00 PM EST

M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers

EUREKALERT

Contact: Robyn Stein
robyn.stein@gabbe.com
212-220-4444
University of Texas M. D. Anderson Cancer Center

Best practices in cancer screening translated into risk-based guidelines for the public

HOUSTON - Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.

The new recommendations represent the first wave of an effort by M. D. Anderson to improve the effectiveness of efforts to prevent and detect cancer at its earliest, most treatable stage by reconstructing and expanding its screening, risk reduction and diagnostic guidelines across eight disease sites.

Available on M. D. Anderson's Web site, the recommendations translate best practices in cancer prevention employed at M. D. Anderson into accessible guidelines the public can follow, with risk categories identified and information about when to begin and discontinue screening exams.

According to the American Cancer Society, more than 40 percent of Americans will develop cancer during their lifetime, and cancers that can be prevented or detected earlier by screening account for at least half of all new cancer cases.

"Cancer screening is not one-size-fits-all," said Therese Bevers, M.D., medical director of M. D. Anderson's Cancer Prevention Center. "Our new risk-based recommendations are markedly more personalized and precise, offering detailed guidance than what has previously been made available to the public here or by other cancer organizations."

Until now, cancer screening recommendations were targeted largely to individuals at average risk for developing cancer based on characteristics like age, family history or genetic predisposition. However, average risk was not previously defined and recommendations for individuals at increased or high risk were not outlined. The new screening guidelines define risk and offer recommendations for those at increased and high risk of developing cancer. For example, there are now five different sets of screening recommendations for those at increased risk for breast cancer; four categories of age-based risk recommendations for cervical cancer; and for colorectal cancer, there are three categories defining those at increased risk and three categories defining those at high risk.

The new guidelines build on established cancer screening practices and now more specifically offer the following recommendations:

Breast Cancer

Starting at age 20, women at all risk levels should practice breast self-awareness by being familiar with how their breasts look and feel and immediately reporting any changes to their doctor. Women aged 40 years and older at average risk should get annual mammograms and breast exams.

For women at increased risk, the type and frequency of exams - including clinical breast exams, mammograms and breast MRI - depend on factors putting them at increased risk, including:

  • history of radiation treatment to the chest;
  • genetic predisposition;
  • diagnosis of lobular carcinoma in situ;
  • Gail Model score of greater than 1.7 percent;
  • or family history.

Cervical Cancer

For women at average risk, it is now recommended that women under age 21 get a liquid-based Pap test within three years of initiating vaginal intercourse. She should continue to have Pap tests annually until she has had three consecutive negative test results. After that, M. D. Anderson recommends screening every two years unless she is at increased risk of cervical cancer based on risk factors, including:

  • history of cervical cancer or severe cervical dysplasia;
  • persistently testing positive for Human Papilloma Virus (HPV);
  • exposure to diethylstilbestrol (DES) before birth;
  • Human Immunodeficiency Virus (HIV) infection;
  • or an immune system that does not function properly.

Beginning at age 30, adding HPV testing is a preferred option to the Pap test, and if both are negative, a woman may go to every three years unless she is at increased risk based on the risk factors cited above or unless the optional HPV test was not done.

Colorectal Cancer

M. D. Anderson recommends a colonoscopy every 10 years (preferred screening), a virtual colonoscopy every five years, or a yearly Fecal Occult Blood Test (FOBT) for men and women aged 50 years and older who are at average risk. For men and women at increased or high risk, the type and frequency of exams - including colonoscopy and flexible sigmoidoscopy - depend on the following factors:

  • personal history of precancerous (adenomatous) polyps;
  • personal history of colorectal cancer;
  • family history of colorectal cancer or precancerous (adenomatous) polyps;
  • genetic diagnosis of Familial Adenomatous Polyposis;
  • genetic history of Hereditary Nonpolyposis Colorectal Cancer or a clinical history suggesting such;
  • or inflammatory bowel disease (ulcerative colitis or Crohn's disease).

"Because of the research being conducted in laboratories and clinics at M. D. Anderson and around the world, our understanding of how cancer develops and spreads is steadily increasing," said Ernest T. Hawk, M.D., M.P.H., vice president for Cancer Prevention and Population Sciences.

More knowledge about how doctors make decisions about risk levels and screening tests will give patients a deeper understanding of the disease process and enable them to put their own cancer risk in perspective, he added.

"For colorectal cancer screenings, patients need to be proactive about obtaining results from their screening tests. For example, if a colonoscopy reveals polyps, it is critical for the patient to know what kind, how many and what size, since this information factors heavily into what risk category they fall into for colorectal cancer," Bevers said.

The risk categories and related guidelines were developed by multidisciplinary panels of M. D. Anderson disease site experts across several areas, including: medical oncology, surgical oncology, cancer prevention, imaging and others. Risk-based screening guidelines for prostate, liver, skin, endometrial and ovarian cancers are currently in development and a new online risk assessment tool integrating the new screening guidelines will be launched on the M. D. Anderson Web site in early 2010.

M. D. Anderson established the Division of Cancer Prevention and Population Sciences in 1994 and was among the first Comprehensive Cancer Centers (a National Cancer Institute designation) to launch a broad, multifaceted cancer prevention program. Today, the division of serves as a model for other prevention programs, nationally and internationally.

About M. D. Anderson

The University of Texas M. D. Anderson Cancer Center in Houston ranks as one of the world's most respected centers focused on cancer patient care, research, education and prevention. M. D. Anderson is one of only 40 comprehensive cancer centers designated by the National Cancer Institute. For six of the past eight years, including 2009, M. D. Anderson has ranked No. 1 in cancer care in "America's Best Hospitals," a survey published annually in U.S. News & World Report.

Breast, Cervical and Colorectal Cancer Statistics

In 2009, the American Cancer Society estimated:

  • New cases of breast cancer will be diagnosed in 192,370 women and 40,170 will die from breast cancer;
  • 11,270 new cases of cervical cancer will be diagnosed in women and 4,070 women will die from cervical cancer;
  • New cases of colorectal cancer will be diagnosed in 106,100 men and women and 49,920 men and women will die from colorectal cancer.

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Boo! Woman charged with stealing from haunted house - Cincinnati.com

Posted: 26 Oct 2009 10:30 AM PDT

A 33-year-old Green Township woman is accused of cheating a Dent haunted house out of nearly $7,500 by carrying out a scheme to re-sell stolen tickets to the attraction for cash, according to Green Township police.

Not only did Nikki Hill prey on the Dent School House Haunted House, she then duped innocent buyers at a table outside the nearby Kroger store, telling them the tickets were discounted and that she would donate 50 percent of the proceeds to breast cancer research, police said.

Hill faces a felony charge of receiving stolen property after she was caught Sunday selling the tickets.

After a court appearance this morning, Hill explained she bought the tickets on the Web site Craigslist from a man who told her he worked at the haunted house and was compensated with tickets to the attraction. Hill had 529 entrance tickets valued at $7,470, police said.

The tickets went missing during a break-in, police said.

"The defendant stated it seemed odd to her that she was able to buy that amount of tickets for so cheap, however she thought it would be a quick way to make money," officers wrote in court records.

Hill was released without bond because the jail was too crowded.



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Don’t ever give up, survivor advises - Stillwater News Press

Posted: 26 Oct 2009 09:11 AM PDT

Published: October 26, 2009 11:09 am print this story

Don't ever give up, survivor advises

Darla Slipke

One of the things Connie Garst dreaded most when she found out she had breast cancer was telling her family.

Still, she was glad to have her husband with her when doctors made the diagnosis in March 2000.

"Just hearing the word cancer is a scary experience in itself," Garst said.

Right away, she was faced with many critical decisions, including when and where to seek treatment. Garst had a lumpectomy, followed by eight chemotherapy infusions in seven months and 37 radiation treatments on weekdays.

After she lost her hair, Garst said, she never let anyone — even her husband — see her without a wig or some sort of head covering.

One time her husband came home unexpectedly and caught her in the kitchen. Garst said she grabbed a dish towel and covered her head. Looking back now, she laughs about the incident.

Prayer and faith were important to her recovery, Garst said.

"Some of the highest points were just knowing that God was there," he said.

Cards, calls and support from friends and family also meant a lot. Their constant support helped her to keep a positive attitude — something Garst said is always important during difficult times.

She encouraged anyone who is facing cancer to never give up.

"There's a lot of successes in breast cancer now," she said. "Even in the nine years since I was diagnosed, they've come a long way."

Since her recovery, Garst said, she has had the privilege of talking to many cancer victims to offer advice or encouragement.

"I've found there's a special bond between us, and it doesn't matter what kind of cancer," she said.

For several years, she and a friend, who also overcame cancer, hosted a support group at Sunnybrook Christian Church.

People still approach Garst to ask about her experiences.

"I still get calls from people, friends, who say, 'My friend or my sister has breast cancer. Can I call you?'" she said. "And that's always fine with me. I'm willing to talk to anybody. If it helps, that's fine with me."

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The White House gets a Pink Ribbon (breast cancer awareness) - pics - Democratic Underground.com

Posted: 26 Oct 2009 09:25 AM PDT


Workers install a pink ribbon in to promote awareness of breast cancer on the front of the White House in Washington, October 26, 2009.
REUTERS/Jonathan Ernst (UNITED STATES POLITICS HEALTH SOCIETY)


Workers hoist a pink ribbon in honor of breast cancer awareness on the front of the White House in Washington, October 26, 2009.
REUTERS/Jonathan Ernst (UNITED STATES POLITICS HEALTH SOCIETY)


A pink ribbon to recognize breast cancer awareness is being hung on the north portico of the White House in Washington Monday, Oct. 26, 2009.
(AP Photo/Alex Brandon)


A Uniformed Secret Service officer watches as a pink ribbon to recognize breast cancer awareness is hung on the north portico of the White House in Washington, Monday, Oct. 26, 2009.
(AP Photo/Alex Brandon)


Members of the media look on as workers lift a giant pink ribbon into place on the North Portico of the White House in Washington, DC, in support of Breast Cancer Awareness Month October 26, 2009.

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Industry roundup - ADOTAS

Posted: 26 Oct 2009 09:11 AM PDT

Written on
October 26th 2009
Author
by Gavin Dunaway |
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roundup_smallADOTAS - Mobclix has formed partnerships with Advertising.com and Traffic Marketplace that will provide the advertising networks direct access to mobile audiences.

Razorfish might be heading over to Publicis Groupe's inner sanctum, but Jeff Lanctot, the veteran chief of media buying strategy, is going to stay at Microsoft in the Advertiser and Publisher Solutions group. Lanctot reportedly will manage Microsoft's long-term media and services agreement with Publicis Groupe.

Aedgency has added three executives in newly created positions — Christophe Philip will be head of operations; James Applin has joined as sales manager for the United Kingdom; and Philippe Morin has been recruited as head of price comparison.

SearchForce has launched an auto-generated, overall performance summary to aid search marketers and agencies with a simpler workflow and reporting solution.

Constant Contact has released an online event marketing service to help small businesses and organizations professionally promote and efficiently manage registrations and RSVPs for meetings, functions, seminars and other events.

SWIRE has opened offices in the Washington, D.C. area and Denver and has hired Steven Seybold as interactive creative director to lead the Denver office.

Blue Barracuda has hired Ken Cheung to lead its affiliate marketing effort. Cheung was formerly head of affiliates at Altogether Digital.

The Atlantic has named Breda O'Reilly digital ad manager. Previously O'Reilly was a strategic account executive with Microsoft Advertising.

RP3 Agency has produced an online animated public service announcement pro bono for the Washington Area Woman's Foundation's Annual Leadership Luncheon. Razorfish managing director Jim Watson will also stay with big MS with a new position in the audience segment business.

In honor of Breast Cancer Awareness Month, Cosmopolitan magazine launched the Cosmo Karma Project, a multiplatform social media initiative sponsored by Estée Lauder encouraging and rewarding readers for performing small acts of kindness. The site will benefit the Breast Cancer Research Foundation.

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