Thursday, October 15, 2009

“Bus driver suspended for wearing pink tie - WLS” plus 4 more

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“Bus driver suspended for wearing pink tie - WLS” plus 4 more


Bus driver suspended for wearing pink tie - WLS

Posted: 15 Oct 2009 07:44 AM PDT

A Springfield Mass Transit District bus driver has received a one-day unpaid suspension for wearing a pink necktie to help raise awareness for breast cancer.

The driver, 46-year-old William Jones, had to serve the suspension, but his action led the transit district to agree that employees could wear pink on Fridays October in recognition of National Breast Cancer Awareness Month.

Jones, who said he planned to file a formal grievance, said he has had a number of relatives who have battled cancer, including a grandmother, a sister, several cousins and a niece.

Linda Tisdale, the district's managing director, said employees must ask in advance before wearing any deviation from the standard uniform.

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Transcendental meditation reduces stress, improves mental health among ... - Genetic Engineering News

Posted: 13 Oct 2009 01:59 PM PDT

INTERVIEW: BIOMOLECULAR COMPUTATION - Interview with Erik Winfree, Ph.D., Associate Professor of Computer Science, Computation and Neural Systems, and Bioengineering, California Institute of Technology ...MORE

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Ohio wife, husband both battling breast cancer - WTOP Radio

Posted: 12 Oct 2009 12:05 PM PDT

MONROE, Ohio (AP) - A husband and wife are both undergoing treatment for breast cancer in a case that illustrates how the disease can strike both sexes. Mike and Barbara Welsh, of Monroe, in southwestern Ohio, each had surgery this year after separate discoveries that they had breast cancer.

Barbara Welsh, 63, had surgery in January, went through chemotherapy and is now starting radiation treatments.

After surgery in July, her 62-year-old husband is determining the next step in his recovery, which may include chemotherapy and radiation. He had a modified radical mastectomy on his right breast.

Mike Welsh says he is speaking up about his cancer to make other men aware that breast cancer is not just something that strikes women.

"If I could help 10 people or 100, that's a start," said Welsh, a retired AK Steel bricklayer.

Male breast cancer is still rare, with about 1,900 cases expected to be diagnosed this year, with about 440 men dying from the illness.

Mike Welsh first noticed something was wrong when he got into his car and felt discomfort as he strapped the seat belt across his chest.

After his wife began her treatments, he asked his doctor if men could get breast cancer. His doctor referred him to the Compton Center at Atrium Medical Center, in Middletown, where he got the diagnosis.

The couple, married 41 years, laugh about their experience to help stave off the depression that sunk in after their diagnoses.

"You've got to laugh at it," Mike Welsh said. "You have good days, bad days and better days. We're having fun with it."

He and his wife joke that she glows from radiation treatment that she has begun.

"I'm going to set her outside for Halloween," Mike Welsh said.

___

Information from: The JournalNews of Hamilton, http://www.journal-news.com/cgi-bin/liveique.acgi$schjnfront?jnfront


(Copyright 2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)

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If you have an event send it to: the411@whas11.com - WHAS 11

Posted: 15 Oct 2009 12:16 PM PDT

Welcome to this week's The 411...The Brown Cancer Center is going pink for National Breast Cancer Awareness Month.

Designers added pink ribbons and bows on the building. And at night the Center will glow pink through the month of October. The American Cancer Society says more than 2800 Kentuckians will be diagnosed with breast cancer this year and more than 3700 in Indiana.

Parents we have something for your little ones....The Louisville Children's Theatre kicks off their 2009-2010 season with the Richard Scarry's classic of Busytown! The show will be October 24th and November 7th at The Kentucky Center, Bomhard Theater. For tickets contact the Kentucky Center box office.

If you have an event for the 411 send it to: the411@whas11.com <mailto:the411@whas11.com>. You need to send it in at least two weeks in advance. With The 411...I'm Sherlene Shanklin with WHAS 11 News.

The 411 Calendar

the411@whas11.com

I'm A Survivor Annual Conference

October 15-17

Louisville Memorial Auditorium, 970 S. 4th Street

For more info call 877-786-8241

Pretrial Publicity: How Much is Too Much?

Thursday, October 15th

Louisville Bar Center, 600 W. Main Street

Reception 5:30pm/Program 6:30pm

Free and open to the public

"Fame"

25th Anniversary of the World Premiere

October 15th-17th

Jeffersonville, IN

7:30pm

Tickets $5 students/$10 adults

For tickets call 812-282-6601

World's Largest Halloween Party

October 15-18

Louisville Zoo

$8 per person

For additional information call 502-459-2181

Gabriel Iglesis at the Improv

October 15th-17th

The Improv, 441 South 4th Street, 2nd Floor

Tickets $19

First Annual Chrysanthemum Festival

Saturday, October 17th

1:00pm-5:00pm

Hidden Hill, Utica, Indiana

"Art on Tap" in support of Music Theatre Louisville and Stage One

Sunday, October 18th

Tickets $50 per person

*Must be 21 to attend

For ticket information call 498-2436

Third Day with Glory Revealed

Saturday, October 17th

7:30pm

Tickets $17

Freedom Hall

For additional information call 800-745-3000

A Night of Gospel Music

Saturday, October 17th

6p-9p

Elizabethtown Christian Academy Sanctuary, 401 W. Poplar Street

$10 in advance/$15 at the door

For additional information call 270-763-6723

*Featuring Tommy Brandy, Julia Royston, Abbey Gregory, Divine Mercy and The Vincents

Stripes

Now thru October 24th

Carnegie Center for Art & History

Tuesday-Saturday

10am-5:30pm

Free admission

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Skin cells may provide early warning for cancer risk elsewhere in body - EurekAlert

Posted: 15 Oct 2009 11:47 AM PDT

[ Back to EurekAlert! ] Public release date: 15-Oct-2009
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Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Cell growth abnormalities predisposing people to cancer show up in cultured skin cells

Berkeley -- While some scientists have argued that cancer is such a complex genetic disease that you'd have to sequence a person's complete genome in order to predict his or her cancer risk, a University of California, Berkeley, cell biologist suggests that the risk may be more simply determined by inexpensively culturing a few skin cells.

Harry Rubin, professor emeritus of molecular and cell biology at UC Berkeley, acknowledges that cancer cells have mutations in hundreds of genes, making it hard to determine which are the key triggers and making prognosis and treatment equally difficult. Even normal tissue differs from person to person because of a myriad of less disruptive mutations and because of different environmental exposures, both of which affect future cancer risk.

But in the September issue of the journal Cancer Epidemiology, Biomarkers and Prevention, Rubin argues that, while it may be hard to dissect the role of each of these mutations, their collective effect should be observable in tissue before any cancers develop.

Specifically, increases in how densely the cells grow, which Rubin argues are a prelude to cancer, may be detectable even before the cancer appears, warning of risks that could be lessened by behavioral changes.

"Over a 50-year career, I've worked with cells transforming (into cancer) in culture and seen the first step in a dynamic way, seen cells continuing to multiply when they should have stopped," Rubin said. "This is the first step in cancer, though not yet cancer, and you can measure these changes quantitatively."

The problem, of course, is that it is impractical to test all the body's tissues to determine whether they have abnormal cell growth. But Rubin has found evidence from other studies that, in some cases, skin fibroblasts show these early changes even before cancer appears in other tissues, such as the colon.

"The abnormal growth behavior of skin fibroblasts in cancer-prone individuals has suggested that, at least in some cases, cancer can be considered a systemic disease and that this difference in the behavior of skin fibroblast cells from such individuals may be a practical basis for prevention, diagnosis and management of the disease," he concluded in his paper.

"It's a great idea, scientifically; the question is, 'Is it there clinically?'" said Douglas Brash, professor of therapeutic radiology, genetics and dermatology at Yale School of Medicine. "This is interesting enough that someone should look to see whether it is clinically reliable."

Dr. Stuart H. Yuspa, co-chief of the Laboratory of Cancer Biology and Genetics at the National Cancer Institute, agreed. "Harry's ideas are always amazing, and I admired the paper," he said. "His idea has scientific support, and if it turned out to be correct, it could be extremely valuable for people, assuming they would want to know their risk."

Rubin bases his argument on various studies over the past 50+ years that show that cancers grow from a larger "field" of abnormally multiplying cells that otherwise look normal. These "field" cells are generally ignored by surgeons when they remove solid cancers - in fact, the large size of the field would make its total removal impossible - but pathologists have shown that the cells are capable of again giving rise to cancers.

"These cells have early mutations that could lead to cancer," Rubin said. "Even though they look normal, they multiply in places where they shouldn't and eventually accumulate enough mutations to form a carcinoma. They are the first stage in cancer, but not cancer."

The inappropriate growth - called cancerization - is a sign that the normal processes that stop growth when cells contact one another have been disrupted, though not fully, because otherwise the cells would invade the underlying connective tissue and become cancerous.

Rubin showed in experiments 15 years ago that if you take cells that grow normally in cell culture and encourage mutations, then select for behavioral abnormalities involving growth, you can get proliferation of cells that behave like cancerization field cells.

Similarly, while normal skin fibroblast cells grow to a certain density and stop, fibroblasts from cancer-susceptible individuals grow to an unusually high density in a Petri dish. That difference between fibroblasts from normal and cancer-susceptible individuals can be amplified to improve identification of those at risk of cancer, Rubin said.

Rubin suspects that the growth change in skin fibroblasts heralds a general change in all the body's epithelial tissue, that is, the tissues that line all the body organs. The most prevalent cancers - including colon, breast, lung, skin, head and neck - arise from epithelial tissue. In certain cancer-prone families, for example, the same mutated gene is found in all tissues, and the fibroblasts grow to high densities in culture, just like epithelial cells in a precancerous field do in the body.

"If this works out after studying a large number of cases, then the people who are found to have a high probability of developing cancer would be more likely to pay attention to their diet, exercise, weight, smoking and behaviors that are known to contribute to an increased risk of cancer," he said. "Basic studies of a cell culture model for field cancerization should reveal the conditions that drive or delay the process and could be applied in prevention of cancer."



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