Friday, September 4, 2009

“HPV vaccine could save women from breast cancer - Newstrack India” plus 4 more

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“HPV vaccine could save women from breast cancer - Newstrack India” plus 4 more


HPV vaccine could save women from breast cancer - Newstrack India

Posted: 03 Sep 2009 11:43 PM PDT

Washington, Sep 4 (ANI): Human papillomavirus (HPV) vaccine can prevent some forms of breast cancer in women and save thousands of lives each year, suggested an Australian study.

 

Researchers at the University of New South Wales used genetic probes to test cancerous breast cells, and found several strains of HPVs, which are known to have a high risk of initiating cancer of the cervix.

 

HPV has a causal role in 90-95 per cent of cervical cancers.

 

Led by Visiting Professor James Lawson at UNSW, the researchers confirmed the presence of high-risk HPV in the nuclei of breast cancer epithelial cells in five (39 per cent) of 13 ductal carcinoma in situ and three (21 per cent) of 14 invasive ductal carcinoma (IDC) breast cancer specimens.

 

Non-invasive or in situ cancers are those confined to the milk-making glands, and do not spread to other parts of the breast or body.

 

Invasive cancers such as IDC are more serious and account for 70-80 percent of all breast cancers.

 

"The finding that high risk HPV is present in a significant number of breast cancers indicates they may have a causal role in many breast cancers. Confirming a cancer-causing role for HPV in some breast cancers establishes the possibility of preventing some breast cancers by vaccination against HPV," said Dr Noel Whitaker, a co-author of the new report.

 

HPVs involvement in breast cancer has long been a topic of controversy, as studies from 15 countries around the world have identified the presence of high-risk types of HPV in breast tissue and breast cancer specimens.

 

However, those studies have also showed widely varying results, with the prevalence of HPV-positive breast cancer in ranging from as low as four per cent to as high as 86 per cent, and have been clouded by difficulties in detecting the virus in breast specimens.

 

Besides, the genetic probe technique used - polymerase chain reaction (PCR) - has been criticized for its propensity for contamination.

 

The technique is based on taking small genetic samples and rapidly copying them to provide a large enough sample to study.

 

The researchers in the new study have dealt with these issues by using a technique (in situ PCR) that avoids cross-contamination and that provides evidence about whether HPV genetic material is present in the nuclei of human breast cancer specimens.

 

They validated their findings by looking for "telltale" changes linked to HPV such as enlarged nucleus surrounded by a characteristic "halo".

 

Now, the researchers are working on a new method that will make testing even quicker, cheaper and simpler.

 

The study has been published in the British Journal of Cancer. (ANI)

 


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Hologic: FDA approves new radiation therapy system - Seattle Times

Posted: 01 Sep 2009 02:27 PM PDT

BEDFORD, Mass. —

Hologic Inc. said the Food and Drug Administration approved a new version of its MammoSite system, which delivers radiation seeds to prevent recurrences of breast cancer.

The agency approved the MammoSite ML radiation therapy system, which allows physicians to better target specific areas of tissue than the original MammoSite system, the company said. MammoSite devices include balloon catheters that are inserted into the body after a tumor has been removed. Inside the catheter is a pellet of radioactive material.

The radiation seed is left inside the body for five days, delivering radiation to the areas the cancer is most likely to return, Hologic said. The treatment is intended to prevent a recurrence while not harming healthy tissue.

Hologic, which makes medical diagnostic products for illnesses affecting women, said the new version of the device will allow therapists to treat patients who are not otherwise good candidates for radiation seeding. It said it will also be usable in more typical cases.

The company said it plans to launch the MammoSite ML by Dec. 26, the end of its fiscal fourth quarter. The original MammoSite device was approved in 2002.

In aftermarket trading, Hologic stock rose 50 cents, or 3 percent, to $16.70. The shares finished at $16.20 Tuesday.



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Breast cancer chemotherapy disrupts sleep - United Press International

Posted: 01 Sep 2009 01:01 PM PDT

SAN DIEGO, Sept. 1 (UPI) -- Repeated chemotherapy treatments can result in progressively worse and more enduring sleep-wake activity rhythms impairments, U.S. researchers said.

Principal investigator Sonia Ancoli-Israel of the University of California San Diego said the findings were not surprising because sleep disturbances are common in cancer patients and 30 percent to 50 percent report insomnia symptoms.

Although most variables returned to baseline levels in the second and third weeks of the first cycle of chemotherapy, circadian -- 24-hour cycles -- impairments were maintained.

"Results of this study suggest that our biological clocks are affected by chemotherapy," Ancoli-Israel said in a statement.

"Our biological clock, or circadian rhythm help keep our bodies in sync with the environment."

During chemotherapy, the biological clock gets out of sync, especially after the first cycle of treatment, but the clock seems to regulate itself after only one cycle. However, with repeated administration of chemotherapy, it becomes more difficult for the biological clock to readjust," the study said.

The finding is published in the journal Sleep.



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Women Who Orgasm During Breastfeeding - Momlogic.com

Posted: 04 Sep 2009 10:41 AM PDT

You don't have to feel ashamed -- it's perfectly natural. An expert tells us why.

Dr. Wendy Walsh: When I was pregnant with my first child, I was hosting a show for TLC called "How'd They Do That?" And every day, my mind was asking the same question about pregnancy and breastfeeding. All my female coworkers became a petri dish for me as I probed their minds for information about what the heck was going on with my body.

I was the most nervous about successfully breastfeeding. Frankly, I had no idea how the two orbs with nerve endings directly connected to some pleasurable southern region could be converted into a cafeteria. One morning, as I sat in the makeup chair with my middle bursting with new life, I posed a seemingly crazy question: Could a woman have an orgasm while breastfeeding?

There was a pause. There was a sly smile from the makeup artist. The hairdresser hooted and hollered. Others just laughed their asses off. But I didn't take my eyes off the makeup artist.

Later, when we were alone, I asked her again. She smiled again. "It's more of a sensuous experience," she said, "not a sexual one. It feels warm and cuddly and pleasurable, but it's different from sex. If you had an orgasm, it wouldn't be on purpose."

Years later, I thought of this conversation. I was in one of my human sexuality classes in my psychology Ph.D. program, and we were learning that the nerve endings in our body can respond to physical stimulation even if our brain is not on board. In this case, we were talking about rape, and the confusing feelings that can happen to victims of rape when during this horrific crime they sometimes experience a spontaneous orgasm. What an awful thought.

When my first daughter was finally born (pried out after 42 weeks in the oven), breastfeeding was anything but pleasurable. I like to call the newborn phase of breastfeeding "the vampire weeks," as that tiny, violent, sucking machine increases milk supply. But after a few months, I realized my makeup artist was right. Totally pleasurable. But a far cry from sexual arousal.

As I continued to nurse, I read far and deep into the benefits of breastfeeding for mother and child. One thing I learned is that prolonged breastfeeding can help reduce your chances of getting breast cancer because it stops your periods and the monthly assault of estrogen on your breasts. That was enough for me, since my mother died of breast cancer. I continued on. I also learned that often babies suckle for comfort rather than from hunger, and that there are psychological benefits to this suckling. That sounded good too.

You saw the title of this article, so you know where I'm going here. I never, ever, mentally connected a breastfeeding experience with a sexual experience. The mental boundary was so great that I was convinced it was impossible. Then one night while I was sleeping, I had one of those fabulous dreams that, if a guy had had it, would have involved moisture. You've heard about them. I woke up from the dream to find that my tiny vampire had been doing some nocturnal suckling while I slept. Let me tell you, the experience totally freaked me out. And that was it. I had a co-sleeping bed beside me after that. I needed that bundle an arm's length away.

Later, in another human sexuality class, I asked my professor about this experience. She confirmed that it is possible and probably quite common, although people have feelings of shame about it. Pleasurable breastfeeding was probably one of nature's ways to make a survival behavior attractive. She also told me that many women quit breastfeeding for this reason. For some women, the feelings of an infant suckling can be so pleasurable that they feel it is somehow wrong. That made me feel sad too. Breastfeeding is not pedophilia. Nature brought mommies and babies together for one of the most physically pleasurable relationships on earth. Let them suckle -- and do enjoy it, ladies. It is such a short period in both of your lives. And if your body responds without your consent, relax. Just buy a co-sleeper bed.



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Landmark ruling orders transsexual prisoner to be transferred to women ... - CJAD

Posted: 04 Sep 2009 09:51 AM PDT

By: THE ASSOCIATED PRESS

LONDON - A British court issued a landmark ruling Friday, allowing a transsexual prisoner serving life for manslaughter and attempted rape to be transferred to a women's prison.

High Court Deputy Judge David Elvin said the refusal of Justice Secretary Jack Straw and the prison authorities to transfer the 27-year-old was a violation of her human rights.

The prisoner, who began gender reassignment treatment years ago to become a woman, was not named to protect her identity.

Keeping her in a male prison "effectively bars her ability to qualify for surgery, which interferes with her personal autonomy in a manner which goes beyond that which imprisonment is intended to do," Elvin said.

The prisoner's lawyer, Phillippa Kaufmann, said she would be transferred in the coming weeks.

Although born a man, she began the process of gender reassignment while in prison. In 2006, she obtained a legal acknowledgment that she should be recognized as a woman.

The prisoner, who was then a man, was originally sentenced to five years for manslaughter in 2001 after strangling his boyfriend to death.

Days after his release, he tried to rape a female shopkeeper and was sentenced to life.

The judge said the prisoner had been diagnosed with gender dysphoria and had been aware of her condition from an early age.

In evidence presented for the hearing, she said she had always felt like a woman.

"For me it is simply a reflection of how it should have been from the start," she said, adding she hoped to have surgery soon to remove her penis.

She has adopted a female name, had facial and body hair permanently removed and developed breasts after hormone treatment.

Elvin said she looks "convincingly" like a woman, although she has been prevented from wearing skirts and other items in the male prison.



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