“GateHouse Media New England to ‘Paint the Town Pink’ - Burlington Union” plus 4 more |
- GateHouse Media New England to ‘Paint the Town Pink’ - Burlington Union
- Malignant Signature May Help Identify Patients Likely To Respond To ... - Science Daily
- Obesity, booze up second breast cancer risk - Hindustan Times
- Gatehouse Media New England To "Paint The Town" - Bedford Minuteman
- Opry backdrop to become pink Oct. 2 - WTOP Radio
| GateHouse Media New England to ‘Paint the Town Pink’ - Burlington Union Posted: 10 Sep 2009 07:28 AM PDT GateHouse Media New England (GHMNE) and the Burlington Union have teamed up with the American Cancer Society and We Got Soccer to "Paint the Town Pink" to help raise awareness of the importance of breast cancer prevention, detection and treatment during Breast Cancer Awareness Month. During the week of Sept. 28, GHMNE will print 113 of its newspapers on pink newsprint and will turn all of the Web sites in its WickedLocal.com network pink. The pink newspapers will hit the streets prior to the American Cancer Society's premier event to raise awareness and dollars to fight breast cancer, "Making Strides Against Breast Cancer Walk," Oct. 4 in Boston. GateHouse Media New England's support will commence the "Paint the Town Pink" program with the pink newspapers during the week of Sept. 28 to kick off Breast Cancer Awareness Month. The pink newspawww.cancer.org/stridesonlinepers will carry news content focusing on local stories and people in the communities affected by the disease. The news coverage will continue with local stories and profiles throughout the month of October. "We can't think of a better way to bring attention to such an important cause," said Rick Daniels, GHMNE president. "We are so proud to be supporting this issue in such a dramatic way. The support of our presenting sponsor We Got Soccer helped make this possible," said Daniels. GateHouse Media New England will donate 10 cents from every pink newspaper sold in stores to the American Cancer Society, as well as $5 from any credit card subscription during the month of October. In addition, local businesses can help "Paint the Town Pink" by purchasing a pink ribbon in their ad for $25 and GHMNE will donate that to the American Cancer Society. Advertising packages can also be purchased in print and online and 10 percent of the ad cost will be donated to the American Cancer Society. To participate in the Making Strides Against Breast Cancer Walk, visit www.cancer.org/stridesonline.  This posting includes an audio/video/photo media file: Download Now |
| Malignant Signature May Help Identify Patients Likely To Respond To ... - Science Daily Posted: 09 Sep 2009 11:04 AM PDT ScienceDaily (Sep. 9, 2009) — A molecular signature that helps account for the aggressive behavior of a variety of cancers such as pancreatic, breast and melanoma may also predict the likelihood of successful treatment with a particular anti-cancer drug. The finding, which could lead to a personalized approach to treatment for a variety of solid tumors that are currently resistant to therapies, will be published September 6 in the advance online edition of Nature Medicine. Researchers at the Moores Cancer Center at the University of California, San Diego have discovered that a receptor sitting on the surface of certain aggressive tumor cells can activate a key enzyme, src-kinase, which helps tumor cells become more aggressive in the body. This enzyme is the target of the anticancer drug dasatinib, which blocks its activity and is currently approved for treating chronic myelogenous leukemia (CML). The scientists say that the presence of the receptor – a protein called integrin alpha-v beta-3 – on some of the more common solid tumors such as breast, colon, lung and pancreas could help identify individuals with many other types of cancer that are also likely to respond to the drug. "These results could enable us to identify the subpopulation of cancer patients who are likely to respond to treatment with dasatinib," said David Cheresh, PhD, professor and vice chair of pathology at the UC San Diego School of Medicine and the Moores UCSD Cancer Center, who led the work. "Rather than treat all patients with a given tumor type the same way, by identifying a specific molecular signature consisting of the receptor and its activated enzyme, we can customize the treatment in such a way that we impact the patients most likely to be sensitive to a drug." The researchers compared the growth properties of pancreatic and breast cancer cells that expressed the alpha-v beta-3 receptor versus those that did not, which led to the discovery of a molecular pathway that accounted for the increased malignancy. "Once we identified the pathway, we immediately realized that the drug dasatinib, which targets this pathway, would be a logical choice to use against these cancers," Cheresh said. The group's studies in a preclinical model of pancreatic cancer confirmed that those tumor cells with the receptor responded to the drug, while those not expressing receptors did not. Cheresh pointed to pancreatic cancer tumors, approximately 60 percent of which carry the marker on the tumor cell surface. "We would argue that pancreatic cancer patients with alpha-v beta-3 would respond to dasatinib," he said. Tumors lacking the marker appear to be resistant to the drug. "We discovered an unexpected pathway that accounts for increased malignancy in a population of some of the most dangerous cancers," Cheresh said, noting that the marker could be identified by a biopsy. "There are features of the findings that allow us to implicate dasatinib not just for a single tumor type, but for all tumors with the malignant signature." The findings have led to discussions about the potential design of a clinical trial. "These observations suggest a strategy for testing the effectiveness of dasatinib in breast cancer patients who are positive for the alpha-v beta-3 receptor," said Barbara Parker, MD, medical director of oncology services at the Moores UCSD Cancer Center. Co-authors include: Jay Desgrosellier, PhD, Leo Barnes, David Shields, PhD, Miller Huang, Steven Lau, Nicolas Prevost, David Tarin, MD, and Sanford Shattil, MD.  This posting includes an audio/video/photo media file: Download Now |
| Obesity, booze up second breast cancer risk - Hindustan Times Posted: 10 Sep 2009 03:25 AM PDT Obesity, alcohol use and smoking significantly increase the risk of second breast cancer among breast cancer survivors, says a new study. The study by researchers at Fred Hutchinson Cancer Research Center has been published online in the Journal of Clinical Oncology. "We found that obese women had a 50 per cent increased risk, women who consumed at least one alcoholic drink per day had a 90 per cent increased risk and women who were current smokers had a 120 per cent increased risk of developing a second breast cancer," said lead author Christopher I. Li, M.D., Ph.D., an associate member of the Public Health Sciences Division at the Hutchinson Center. The research suggests that current smokers who imbibe at least seven drinks a week may be at particularly high risk of second breast cancer. "Our study results afford breast cancer survivors three ways to potentially reduce their risk of second cancers: Stay at a normal weight, don't smoke and drink in moderation," he said. Both obesity and alcohol use are associated with increased levels of circulating estrogen and this is thought to be the primary means through which they confer an increased risk of breast cancer, since estrogen can fuel breast cancer growth. The link between smoking and breast cancer may be attributed to carcinogens in tobacco smoke. To reach the conclusion, Li and colleagues assessed body mass index, alcohol use and smoking status in 365 women who were diagnosed with both a first and a second breast cancer and compared them to 726 matched controls diagnosed with only a first breast cancer. Obesity, alcohol use and smoking data were collected from medical record reviews and participant interviews. The study participants, all from the Seattle/Puget Sound region, were first diagnosed with breast cancer between the ages of 40 and 79.  This posting includes an audio/video/photo media file: Download Now |
| Gatehouse Media New England To "Paint The Town" - Bedford Minuteman Posted: 10 Sep 2009 05:55 AM PDT
GateHouse Media New England (GHMNE) and Bedford Minuteman has teamed up with the American Cancer Society and We Got Soccer to "Paint the town Pink" to help raise awareness of the importance of breast cancer prevention, detection and treatment during Breast Cancer Awareness Month. During the week of Sept. 28, GHMNE will print 113 of its newspapers on pink newsprint and will turn all of the Web sites in its WickedLocal.com network pink. The pink newspapers will hit the streets prior to the American Cancer Society's premier event to raise awareness and dollars to fight breast cancer, "Making Strides Against Breast Cancer Walk," Oct. 4 in Boston. GateHouse Media New England's support will commence the "Paint the Town Pink" program with the pink newspapers during the week of Sept. 28 to kick off Breast Cancer Awareness Month. The pink newspapers will carry news content focusing on local stories and people in the communities affected by the disease. The news coverage will continue with local stories and profiles throughout the month of October. "We can't think of a better way to bring attention to such an important cause," said Rick Daniels, GHMNE president. "We are so proud to be supporting this issue in such a dramatic way. The support of our presenting sponsor We Got Soccer helped make this possible," said Daniels. GateHouse Media New England will donate 10 cents from every pink newspaper sold in stores to the American Cancer Society, as well as $5 from any credit card subscription during the month of October. In addition, local businesses can help "Paint the Town Pink" by purchasing a pink ribbon in their ad for $25 and GHMNE will donate that to the American Cancer Society. Advertising packages can also be purchased in print and online and 10 percent of the ad cost will be donated to the American Cancer Society. To participate in the Making Strides Against Breast Cancer Walk go to www.cancer.org/stridesonline.
This posting includes an audio/video/photo media file: Download Now |
| Opry backdrop to become pink Oct. 2 - WTOP Radio Posted: 08 Sep 2009 01:33 AM PDT NASHVILLE, Tenn. (AP) - The Grand Ole Opry in Nashville is joining the fight against breast cancer by "going pink" during two performances Oct. 2. Opry star Carrie Underwood will flip a switch, turning the Opry's signature red barn backdrop pink in support of the groups Women Rock for the Cure and Susan G. Komen for the Cure. The shows will also include performances by Underwood, Terri Clark and others. The live country music show has been presented regularly since 1925. (Copyright 2009 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)
 This posting includes an audio/video/photo media file: Download Now |
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