Saturday, August 29, 2009

“Cancer donation in honour of Allison - This is Dorset” plus 4 more

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“Cancer donation in honour of Allison - This is Dorset” plus 4 more


Cancer donation in honour of Allison - This is Dorset

Posted: 29 Aug 2009 10:34 AM PDT

Cancer donation in honour of Allison

7:00pm Saturday 29th August 2009

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TWO brave children have presented a donation to the Dorset Cancer Centre in honour of their mum.

George, 11 and Grace, eight, handed over a cheque for £786 in memory of Allison Mabey, who was treated at the cancer unit at Poole Hospital during her six-and-a-half-year battle.

The money was donated by friends and family at her funeral.

Allison was diagnosed with breast cancer which, despite operations, chemotherapy and radiotherapy, spread through her body. She lost her courageous battle with the disease at the end of June, aged just 38.

Allison's mum, Thelma Purdy said: "It was a very tough time, but throughout it she remained positive as we all tried to do. We took each day as it came and battled on.

"She was tremendously brave and fought extremely hard – she was absolutely inspirational to anyone in that position."

She praised staff at the day centre adding: "They were not only nurses, they became friends to all of us. They are a terrific bunch of girls in that day centre."

Thelma also told the Echo how important it was to George and Grace that they made the donation personally to "the people who looked after their mummy".

She added: "The children are a credit to her – these two beautiful children she has left are a wonderful legacy."

Allison's sister Leanne Buckland added: "Allison leaves a massive hole in our hearts. We will always remember her infectious smile."


Your Say YourThisisdorset

godzillareturns, poole says...
7:44pm Sat 29 Aug 09

I knew alison she fought so hard to stay with her children and would be so proud of how brave they have been. Well done george and grace xx

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New Target For Treating Breast Cancer Metastasis - Science Daily

Posted: 29 Aug 2009 07:57 AM PDT

ScienceDaily (Aug. 29, 2009) — Dr. Amanda Harvey and colleagues at Brunel University have demonstrated that the protein Brk plays a role in breast cancer progression and dissemination. Their report can be found in the September 2009 issue of the American Journal of Pathology.

Breast cancer metastasis causes nearly 90% of the lethality among breast cancer patients. Non-metastatic breast cancer cells rely on interactions with other cells and the extracellular matrix to survive. Metastatic breast cancer cells must survive in the absence of these interactions.

Harvey et al hypothesized that Brk, a tyrosine kinase expressed predominantly in breast tumors compared with normal breast tissue, plays a role in breast cancer progression by promoting anchorage independence. Indeed, high-grade tumors from human breast cancer patients expressed elevated levels of Brk when compared with lower grade tumors. Inhibiting Brk expression resulted in cell death in the absence of cell-cell and cell-matrix interactions, and tumor cells with increased levels of Brk expression survived without these interactions. These data therefore support a role for Brk in breast cancer progression and dissemination.

Dr. Harvey and colleagues suggest "that Brk plays a role in protecting breast cancer cells from detachment-induced cell death. Therefore, Brk expression in carcinomas may confer a survival advantage on metastasizing tumor cells. … [Future studies will examine] whether this function is manifest in other Brk-positive tumor cells from tissues other than the breast, such as the colon and prostate."


Journal reference:

  1. Harvey AJ, Pennington CJ, Porter S, Burmi RS, Edwards DR, Court W, Eccles SA, Crompton MR. Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage. American Journal of Pathology, 2009, 175: 1226-1234


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Pelotonia riders ready to roll - Columbus Dispatch

Posted: 29 Aug 2009 08:11 AM PDT

After 10 months of planning, the Pelotonia Tour was born last night on the lawn of Chemical Abstracts Service.

The labor of love -- a collaboration between NetJets Inc. and Ohio State University -- continues at the same spot on the Northwest Side this morning when more than 2,250 bicyclists depart on rides ranging from 25 to 100 miles to raise money for cancer research.

"From one cancer survivor to thousands more, I thank you for being here," seven-time Tour de France winner Lance Armstrong told a crowd of about 7,000 last night.

Most were riders and their guests, but quite a few were cancer survivors and patients. All were fed and entertained under threatening skies.

"Everybody here has two things in common," said Armstrong, who survived testicular cancer that spread to his brain and lungs. "We like to ride and we hate cancer."

Armstrong is riding 100 miles to Athens today. He said he plans to stay with the pack as long as possible before pulling away.

"It's not a race, and it's not like I need a good workout," he said, adding that he expects to arrive in Athens around 11:30 a.m. or noon.

About 500 registered riders will bed down in dorms at Ohio University tonight and return Sunday to log another 80 miles to reach Slate Run Metro Park.

Armstrong, who is making a cycling comeback after a three-year retirement and finished third in this year's Tour de France, was joined on stage by Pelotonia Executive Director Tom Lennox, also a cancer survivor; Ohio State President E. Gordon Gee; Gov. Ted Strickland; Columbus Mayor Michael Coleman; and others.

All will be riding but Strickland, who plans to cheer riders when they pass the Statehouse shortly after the 7:15 a.m. start today. Each participant committed to raising between $1,000 and $2,000.

Gee hammed it up by leading an "OH-IO" chant before deadpanning: "I'm damn glad I don't live in Tennessee," a likely reference to his time as chancellor at Vanderbilt University.

On a more serious note, he talked about his first wife dying of breast cancer, part of his motivation to participate.

"It has touched me; it has touched everyone in this country. We're going to cure the damn thing, let me tell you."

Pelotonia organizers hope to raise $4.5 million this year and $40 million over five years for cancer research at OSU's Comprehensive Cancer Clinic, which includes the Arthur G. James Cancer Hospital.

Tour expenses are being underwritten by a $12.5 million donation from NetJets.

Armstrong thanked the sponsors and researchers at the James.

"When we pedal tomorrow, you can think about them and your loved ones," he said to cheers last night.

Pelotonia riders come from Ohio and 30 other states.

They include:

• Ross Chase, 50, who biked 17 miles from his home in Westerville to the Pelotonia kickoff. The father of five said it was a great warmup for the 180 miles he'll ride this weekend.

• Chris Tinko, 16, whose face lit up when he was awarded a framed riding jersey autographed by Armstrong. The Columbus Academy student raised $4,000 in pledges, which made him eligible for the prize.

"This is going to be our generation's problem, so we deserve a chance to fight," he said of his efforts.

• Martha Towslee, 45, and Ken Lorenz, 46, who are celebrating their engagement by riding 180 miles. The Worthington couple bonded over their affinity for cycling and got engaged in March during their first bike trip of the season.

• Dennis King of Manchester in Adams County, who worked a half-day yesterday, then drove to Columbus and signed up for Pelotonia as a rare walkup. He'll ride 180 miles and spend the night in a tent that he plans to pitch in Athens.

"Of course, it would be awesome to meet Lance," he said, "but it's just good to say you're a part of this whole thing."

jsheban@dispatch.com

asudar@dispatch.com



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14 breast cancer surgeries in three-and-a-half hours conducted at ... - New Kerala

Posted: 29 Aug 2009 02:20 AM PDT

Madurai, Aug 29 : Doctors at a hospital in Madurai claimed to have performed breast cancer surgeries on 14 patients within three-and-a-half hours.

Officials at the state-run Rajaji Hospital said the surgeries were performed on August 24 from 8.30 in the morning.
Doctors termed it as a record in medical history.

"We already had seven patients who had to be operated upon initially but in order to create a record in medical history, my colleague doctor Chandrashekhar favoured a surgery for more people so as to make it a record of a dozen patients. But, once we finished 12 cases we planned two more cases and that is how we executed it," said hospital's dean Dr. SM Sivakumar.

Meanwhile, State's health secretary V K Subburaj said that they would not recommend the feat for any record.
"If they have not done it properly, if they have done it with a view to break some record. It is not permissible. We have not permitted them. It has not been done with the permission of the government. We will never send it for any Guinness record. We will never recommend," Subburaj added.

The announcement shocked members of the medical fraternity, including those from the Tamil Nadu State Medical Council and the Indian Medical Association, who called it a blatant violation of the Hippocratic oath.

--ANI




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Raising pink pounds for Welwyn Garden City breast cancer unit - Welwyn & Hatfield Times

Posted: 29 Aug 2009 01:02 AM PDT



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